He was 57.
The funnyman passed away Wednesday morning at a New York City hospital, TMZ reported, citing his manager. He had been undergoing chemotherapy.
Murphy earned a tremendous fan base as a writer for “Chappelle’s Show,” on which he frequently appeared in sketches alongside star Dave Chappelle.
He had a recurring segment on the Comedy Central series called “Charlie Murphy’s True Hollywood Stories,” which featured him comically recalling his unfortunate interactions with major 1980s stars such as Prince and Rick James when he was a member of his brother’s crew.